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Synthesis ofN-substituted 2-(5,6,7,8-tetrafluoro-4-oxo-1,4-dihydroquinolin-3-yl)glyoxylic acids
Authors:G A Obanin  A S Fokin  Ya V Burgart  O V Ryzhkov  Z E Skryabina  V I Saloutin  O N Chupakhin
Institution:(1) Institute of Organic Synthesis, Ural Division of the Russian Academy of Sciences, 20 ul S. Kovalevskoy, 620219 Ekaterinburg, Russian Federation
Abstract:Methods for the synthesis of the earlier unknownN-substituted 2-(5,6,7,8-tetrafluoro-4-oxo-1,4-dihydroquinolin-3-yl)glycoxylic acids their esters from copper chelate of ethyl pentafluorobenzoylpyruvate were developed. The structure of intermediate ethyl 4-(R-amino)-2-oxo-3-pentafluorobenzoylbut-3-enoates is discussed. Published inIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 7, pp. 1234–1239, July, 2000.
Keywords:ethyl pentafluorobenzoylpyruvate  ethyl 4-(R-amino)-2-oxo-3-pentafluorobenzoylbut-3-enoates  3-ethoxalyl-5  6  7  8-tetrafluoroquinolin-4-ones            N-substituted 2-(5  6  7  8-tetrafluoro-4-oxo-1  4-dihydroquinolin-3-yl)glyoxylic acids
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