Interaction of Pd(II) with Glutamic Acid |
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| Authors: | Akat'eva M E Erofeeva O S Dobrynina N A Ivanova N A Efimenko I A |
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| Institution: | (1) Lomonosov State University, Vorob'evy gory, Moscow, 119899, Russia;(2) Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Sciences, Leninskii pr. 31, Moscow, 119991, Russia |
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| Abstract: | Pd(II) complexes with glutamic acid of the composition KPd(HGlu)Cl2] (I) and Pd(HGlu)2] (II) were synthesized and studied by IR and electronic absorption spectroscopy methods. Pd2+–H2O–Cl– and Pd2+–H2O–Cl––H2Glu systems were analyzed by pH-metric titration. The most essential Pd(II) complex forms were established by mathematical modeling and their formation constants were calculated. The electronic absorption spectra of complexes I and II were measured in aqueous and physiological solutions. Complex I was found to be biologically active and to exhibit antimetastatic properties. |
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