Cleavage of a DNA fragment by a binary oligonucleotide reagent |
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| Authors: | S. I. Oshevski |
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| Affiliation: | (1) Siberian Branch of the Russian Academy of Sciences, Institute of Cytology and Genetics, 10 prosp. Akad. Lavrent"eva, 630090 Novosibirsk, Russian Federation |
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| Abstract: | ![]()
The possibility of specific cleavage of a single-stranded DNA fragment due to cooperative action of two oligonucleotide derivatives bearing chemical groups (at the 3"-phosphate and 5"-thiophosphate ends, respectively) located close to each other in a complementary complex is demonstrated. |
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| Keywords: | oligonucleotide derivatives specific cleavage of single-stranded DNA binary oligonucleotide reagent |
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