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Design,synthesis and biological evaluation of 3,4-dihydronaphthalen-1(2H)-one derivatives as Bcl-2 inhibitors |
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| Authors: | Wang Fuli Zhang Rongxiang Cui Yong Sheng Liping Sun Yinping Tian Wei Liu Xiao Liang Shuzeng |
| Affiliation: | 1.Department of Oncology, The Central Hospital of Zibo, Zibo, 255036, Shandong, People’s Republic of China ;2.Department of Outpatient Service, The Shouguang People’s Hospital, Shouguang, 262799, Shandong, People’s Republic of China ;3.Department of Oncology, The Shouguang People’s Hospital, Shouguang, 262799, Shandong, People’s Republic of China ;4.Outpatient Operating Room, The Shouguang People’s Hospital, Shouguang, 262799, Shandong, People’s Republic of China ;5.Operating Room, Qianfoshan Hospital Affiliated to Shandong University, Jingshi Road, Lixia District, Jinan, 250014, Shandong, People’s Republic of China ; |
| Abstract: | Research on Chemical Intermediates - A series of new 3,4-dihydronaphthalen-1(2H)-one derivatives (6a–f) were designed, and synthesized by the Claisen–Schmidt condensation reaction.... |
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