Detection of new radiolysis products in γ-irradiated,methanolic medazepam by GC-FTIR |
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| Authors: | I A Werner H Altorfer X Perlia |
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| Institution: | (1) Department of Pharmacy, ETH Zurich, Leonardstr. 27, CH-8092 Zurich |
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| Abstract: | Summary A methanolic solution of 2% medazepam was irradiated with a dose of 50 kGy. A capillary gas chromatograph with a Fourier Transformation
Infrared Spectrophotometer (FTIR) was used to investigate the radiolysis products in the solution. The changed products found
earlier were confirmed and new ones identified. The radiolytic scheme can be improved and enlarged. |
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| Keywords: | Gas chromatography FTIR γ -Irradiation sterilization Medazepam 1 4-Benzodiazepines |
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