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1H and 13C NMR spectral assignment of androstane derivatives |
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| Authors: | Fuente Ariadna Reyes Mayra Alvarez Yoanna M Ruiz José A Vélez Hermán Viñas-Bravo Omar Montiel-Smith Sara Meza-Reyes Socorro Sandoval-Ramírez Jesús |
| Affiliation: | Centro de Química Farmacéutica, Apartado Postal 16042, Ciudad de La Habana, Cuba. |
| Abstract: | (1)H and (13)C NMR spectroscopic data for 5alpha-androstanes and halo-5alpha-androstanes with different substituents at positions C-3, C-9, C-11 and C-17 were examined and assigned by a combination of 1D and 2D NMR experiments. The substituent effects on the (13)C chemical shifts were compared with those of epi-androsterone, used as a reference compound. The coupling constants (n)J((19)F,(13)C) were measured for compounds 6, 8, 11 and 14. |
| Keywords: | NMR 1H NMR 13C NMR 5α‐androstanes halo‐5α‐androstanes |
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