Pd-catalyzed C-h fluorination with nucleophilic fluoride |
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| Authors: | Kate B McMurtrey Joy M Racowski Melanie S Sanford |
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| Affiliation: | University of Michigan , Department of Chemistry, 930 North University Avenue, Ann Arbor, Michigan 48109-1055, United States. |
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| Abstract: | ![]()
The palladium-catalyzed C-H fluorination of 8-methylquinoline derivatives with nucleophilic fluoride is reported. This transformation involves the use of AgF as the fluoride source in combination with a hypervalent iodine oxidant. Both the scope and mechanism of the reaction are discussed. |
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