无气味的1-（1, 3-二噻-2-亚基）丙酮作有效的1, 3-丙二硫醇替代试剂的缩硫醛/酮化反应

在常温1-（1, 3-二噻-2-亚基）丙酮1f是无气味的、稳定的白色固体，它易通过易制备的3-（1, 3-二噻-2亚基）-2, 4-戊二酮1b的酸性条件下的脱乙酰化反应制得，产率为86%。在MeCOCl/MeOH体系中，在常温和回流条件下，1f能作为有效的1, 3-丙二硫醇替代试剂与醛和酮进行缩硫醛/酮化反应，高产率（86-99%）合成1, 3-二噻烷衍生物。与已报道的硫醇替代试剂1a-e相比，在缩硫醛/酮化反应中1f是活性最好的1, 3-丙二硫醇替代试剂。

Thioacetalization Reaction of Odorless 1-(1, 3-dithian-2-ylidene)

1-(1, 3-dithian-2-ylidene)propan-2-one 1f, which is odorless and steady white crystal at room temperature, was prepared readily in 86% yield via decarbonylation of 3- (1, 3-Dithian-2-ylidene)-pentane-2,4-Dione 1b under acidic condition. Thioacetalization reactions of odorless 1-(1, 3-dithian-2-ylidene)propan-2-one as efficient 1, 3-propandithiol equivalent with selected aldehydes and ketones were carried out at room and reflux temperature in the present of MeCOCl in MeOH, and 1, 3-dithiane derivatives were obtained in excellent yield (86-99%). Compared with reported 1a-e, 1f is regarded as optimal 1, 3- propandithiol equivalent in thioacetalization reaction.