首页 | 本学科首页   官方微博 | 高级检索  
     检索      


Synthesis of a new insoluble polymer-supported chiral alcohol auxiliary and its first application to nucleophilic addition to ketenes
Authors:Akkari R  Calmes M  Mai N  Rolland M  Martinez J
Institution:Laboratoire des Amino acides, Peptides et Protéines, UMR-CNRS 5810-Universités Montpellier I et II, Place Eugène Bataillon, 34095 Montpellier Cedex 5, France.
Abstract:The preparation of a new optically active alcohol with a carboxylic function that allowed its attachment to an amine-functionalized insoluble polymer is described. Its first use as a polymer supported chiral auxiliary is demonstrated by asymmetric transformation of two racemic aryl propionic acids via ketene formation (95-96% ee).
Keywords:
本文献已被 PubMed 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号