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A highly organocatalytic stereoselective double Michael reaction: efficient construction of optically enriched spirocyclic oxindoles
Authors:Wang Liang-Liang  Peng Lin  Bai Jian-Fei  Jia Li-Na  Luo Xi-Ya  Huang Qing-Chun  Xu Xiao-Ying  Wang Li-Xin
Institution:Key Laboratory of Asymmetric Synthesis and Chirotechnology of Sichuan Province, Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041, China.
Abstract:An effective double Michael reaction has been disclosed to access spirocyclic oxindoles in high yields (up to 98%) and excellent enantioselectivities (up to 98% ee).
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