Lewis base activation of Lewis acids: development of a Lewis base catalyzed selenolactonization |
| |
| Authors: | Denmark Scott E Collins William R |
| |
| Affiliation: | Roger Adams Laboratory, Department of Chemistry, University of Illinois, 600 South Mathews Avenue, Urbana, Illinois 61801, USA. denmark@scs.uiuc.edu |
| |
| Abstract: | The concept of Lewis base activation of Lewis acids has been applied to the selenolactonization reaction. Through the use of substoichiometric amounts of Lewis bases with "soft" donor atoms (S, Se, P) significant rate enhancements over the background reaction are seen. Preliminary mechanistic investigations have revealed the resting state of the catalyst as well as the significance of a weak Br?nsted acid promoter. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
