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| 单核铜配合物Cu(C_(16)H_(13)N_2OS_2)_2的合成、晶体结构和生物活性(英文) | |
| 引用本文： | 仇晓阳,刘 瑛,程 艳,郑 昕,朱海亮.单核铜配合物Cu(C_(16)H_(13)N_2OS_2)_2的合成、晶体结构和生物活性(英文)[J].无机化学学报,2010,26(8):1485-1489. |
| 作者姓名： | 仇晓阳 刘 瑛 程 艳 郑 昕 朱海亮 |
| 作者单位： | 1. 商丘师范学院化学系,商丘,476000;医药生物技术国家重点实验室,南京,210093 2. 商丘师范学院化学系,商丘,476000 3. 医药生物技术国家重点实验室,南京,210093 |
| 基金项目： | 河南省教育厅项目，安徽省教育厅项目 |
| 摘 要： | A planar copper complex Cu(L)2,HL=(E)-benzyl-2-(4-formylbenzylidene)-Hydrazinecarbodithioate,has been prepared via the template effect of copper ion. Crystal structure of the complex was determined by X-ray singlecrystal diffraction analysis. The crystal data for this complex:Orthorhombic,space group Pbcn,a=2.250 0(14) nm,b=1.660 0(11) nm,c=0.830 4(5) nm,V=3.102(3) nm3,Z=4,μ=1.011 mm-1,Dc=1.478 g·cm-3,F(000)=1 420,R1= 0.050 1,wR2=0.087 2 (observed reflections with I2σ(I)) and R1=0.129 1,wR2=0.100 9 (all reflections) GOF= 1.011. In the compound,Cu(Ⅱ) atom is four-coordinated with two N atoms and two S atoms from two bidentate ligands and located in the inversion center. The preliminary bioassay indicates that the complex exhibits distinct antitumor activity. |
| 关 键 词： | 铜配合物 平面结构 晶体结构 生物活性 |
Synthesis, Crystal Structure and Biological Activity of a New Mononuclear Copper Complex Cu(C16H13N2OS2)2 |
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| QIU Xiao-Yang,LIU Ying,CHENG Yan,ZHENG Xin and ZHU Hai-Liang.Synthesis, Crystal Structure and Biological Activity of a New Mononuclear Copper Complex Cu(C16H13N2OS2)2[J].Chinese Journal of Inorganic Chemistry,2010,26(8):1485-1489. | |
| Authors: | QIU Xiao-Yang LIU Ying CHENG Yan ZHENG Xin and ZHU Hai-Liang |
| Institution: | Department of Chemistry, Shangqiu Normal University, Shangqiu, Henan 476000; State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093,Department of Chemistry, Shangqiu Normal University, Shangqiu, Henan 476000,Department of Chemistry, Shangqiu Normal University, Shangqiu, Henan 476000,Department of Chemistry, Shangqiu Normal University, Shangqiu, Henan 476000 and State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093 |
| Abstract: | A planar copper complex Cu(L)2, HL=(E)-benzyl-2-(4-formylbenzylidene)- Hydrazinecarbodithioate, has been prepared via the template effect of copper ion. Crystal structure of the complex was determined by X-ray single-crystal diffraction analysis. The crystal data for this complex: Orthorhombic, space group Pbcn, a=2.250 0(14) nm, b=1.660 0(11) nm, c=0.830 4(5) nm, V=3.102(3) nm3, Z=4, μ=1.011 mm-1, Dc=1.478 g·cm-3, F(000)=1 420, R1=0.050 1, wR2=0.087 2 (observed reflections with I>2σ(I)) and R1=0.129 1, wR2=0.100 9 (all reflections) GOF=1.011. In the compound, Cu(Ⅱ) atom is four-coordinated with two N atoms and two S atoms from two bidentate ligands and located in the inversion center. The preliminary bioassay indicates that the complex exhibits distinct antitumor activity. CCDC: 763155. |
| Keywords: | Schiff base crystal structure biological activity |
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