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| 考虑冷热刀刀头温度响应对制定肿瘤治疗计划的影响 | |
| 引用本文： | 邓中山,刘静,周一欣. 考虑冷热刀刀头温度响应对制定肿瘤治疗计划的影响[J]. 工程热物理学报, 2006, 27(Z2): 41-44 |
| 作者姓名： | 邓中山 刘静 周一欣 |
| 作者单位： | 中国科学院理化技术研究所,北京,100080 |
| 基金项目： | 国家自然科学基金;中国科学院院长基金 |
| 摘 要： | 本文对冷热联合治疗肿瘤过程中在体生物组织的温度响应进行了深入的数值研究。组织被当作非理想材料,在一定的温度范围内冷冻和融化,并且考虑了未冻结组织和未损伤组织区域的血液灌注及代谢产热的影响。对比考虑和不考虑冷热刀刀头温度响应两种情形的计算结果表明,拟定治疗计划中若不考虑刀头温度响应,则有可能会造成冷热剂量的不足,从而无法彻底杀灭肿瘤。 |
| 关 键 词： | 低温手术 热疗 治疗计划 肿瘤 生物传热 |
| 文章编号： | 0253-231X(2006)Suppl.2-0041-04 |
| 修稿时间： | 2006-01-24 |
THE EFFECT OF CONSIDERING TEMPERATURE RESPONSE OF CRYOPROBE ON TREATMENT PLANNING FOR TUMOR |
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| DENG Zhong-Shan,LIU Jing,ZHOU Yi-Xin. THE EFFECT OF CONSIDERING TEMPERATURE RESPONSE OF CRYOPROBE ON TREATMENT PLANNING FOR TUMOR[J]. Journal of Engineering Thermophysics, 2006, 27(Z2): 41-44 | |
| Authors: | DENG Zhong-Shan LIU Jing ZHOU Yi-Xin |
| Abstract: | Abstract In this article, the temperature responses of in vivo biological tissues during the combined cryosurgery and hyperthermia treatments for tumor were studied through extensive numerical simulations. The tissues were treated as nonideal materials, freezing/thawing over a temperature range, and the effects of blood perfusion and metabolic heat generation in the unfrozen and undamaged tissues were also taken into account. It was indicated through comparing the computational results for the cases of considering and without considering the temperature response of cryoprobe that, inadequate cooling/heating dosages may be resulted if without considering the temperature response of cryoprobe in treatment planning, and then contributing to incomplete tumor-killing. |
| Keywords: | cryosurgery hyperthermia treatment planning tumor bioheat transfer |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |