Zn2+-dependent peptide nucleic acids probes |
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Authors: | Mokhir Andriy Krämer Roland Wolf Helena |
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Institution: | Ruprecht-Karls-Universitaet Heidelberg, Im Neuenheimer Feld 270, D-69120 Heidelberg, Germany. andriy.mokhir@urz.uni-heidelberg.de |
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Abstract: | Binding of bis-picolylamine-naphthalene diimide-peptide nucleic acid conjugates to complementary DNA is strongly dependent upon Zn2+; ultimately, hybridization is switched ON in the presence muM Zn2+. |
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