Sulfone coupling and double-elimination strategy for carotenoid synthesis |
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Authors: | Guha Samar Kumar Koo Sangho |
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Institution: | Department of Chemistry, Myong Ji University, Yongin, Kyunggi-Do 449-728, Korea. |
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Abstract: | Reaction: see text]. A highly efficient synthetic method of carotenoid compounds has been developed on the basis of the sulfone coupling and double-elimination strategy. This method highlighted the sulfone-mediated coupling with the novel C(10) dialdehyde, 2,7-dimethyl-4-octenedial, which was easily prepared and efficiently utilized in the synthesis of the conjugated polyene chains. |
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