不同品质怀地黄中金属元素含量的ICP-MS测定及其比较

采用湿法消解对不同品质的怀地黄样品进行处理，利用ICP-MS测定不同品质生(干)怀地黄与相应水蒸法炮制熟地黄中多种金属元素含量。结果表明，不同品质地黄及其炮制加工的熟地黄之间金属元素含量无明显差异; 熟地黄中含有Zn, Cu, Cr, Fe, Mn, Sn, Ni, Mo, Co等人体必需的多种微量元素，其中Ca，Fe，Al，Zn，Cu含量较高;不同品质生地黄中对人体健康有利的金属元素含量相对低于其相应品质炮制产物熟地黄。地黄中含有的Co, Ni, Cr, Mn等虽为人体所必需，但超过一定量对人体会产生毒害作用;而Pb等则是对人体有害的微量元素，应该在地黄炮制工艺中注意控制或降低消除此类元素。不同品质地黄中金属元素含量的测定可以为地黄及其炮制加工产物的综合评价提供有益参考。

Determination and Comparison of Metal Elements in Huai Radix Rehmanniae at Different Grades by ICP-MS

The Huai radix rehmanniae at different grades was pretreated by wet digestion,and then the metal elements in the radix rehmanniae and the prepared sample by steaming method were determined using ICP-MS.The results indicate that there is no obvious difference in the metal elements between the different grades and between the dried radix rehmanniae and its corresponding prepared product.There are elements Zn,Cu,Cr,Fe,Mn,Sn,Ni,Mo,Go,etc.in radix rehmanniae,among which the contents of Ca,Fe,Al,Zn and Cu are hig...