Synthesis of a new class of acyclic 2′,5′- and 3′,5′-oligonucleotide analogs based on 9-[1,5-dihydroxy-4(S)-hydroxymethyl-3-oxapent-2(R)-yl]-adenine |
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Authors: | Sergey N Mikhailov Wolfgang Pfleiderer |
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Institution: | 1. Institute of Molecular Biology of the USSR Academy of Sciences, Moscow B-334 / USSR;2. Department of Chemistry, University of Konstanz, P.O. Box 5560, D-7750 Konstanz/W. Germany |
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Abstract: | The acyclic analogs of 2′,5′- and 3′,5′-oligoadenylates possessing all functional groups of the natural compounds were prepared on the basis of “oxydized-reduced” adenosine. |
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