Synthesis of novel chiral bisazetidines by the hydroalane reduction of bis-beta-lactams |
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Authors: | Iwao Ojima Takehiko Yamato Kazuaki Nakahashi |
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Institution: | Department of Chemistry, State University of New York at Stony Brook, Stony Brook, New York 11794, U.S.A. |
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Abstract: | A series of novel chiral bisazetidines in which two azetidine rings are either directly connected or coupled in tandem style, are synthesized in good yields by the hydroalane reduction of the corresponding bis-beta-lactame. |
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