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Synthesis of riccardin B by nickel-catalyzed intramolecular cyclization |
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| Authors: | Masahiko Iyoda Masahiro Sakaitani Hiroki Otsuka Masaji Oda |
| Affiliation: | Department of Chemistry, Faculty of Science, Osaka University, Toyonaka, Osaka 560, Japan |
| Abstract: | Riccardin B, a macrocyclic bis(bibenzyl) possessing cytotoxic activity, and its dehydroxy derivative were synthesized in high yields using the nickel-catalyzed intramolecular coupling of the acyclic precursors. |
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