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Enantioselective microbial hydroxylation of bicyclo(2.2.1)heptane carbon skeleton
Authors:Yoshimitsu Yamazaki  Hidekatsu Maeda
Institution:Fermentation Research Institute, Agency of Industrial Science and Technology, Tsukuba, Ibaraki 305, Japan
Abstract:Bicyclo(2.2.1)heptane-7-carboxylic acid (9) and methyl bicyclo(2.2.1)hept-2-ene-7-syn-carboxylate (5) were microbiologically hydroxylated to give (1R)-2-hydroxy derivatives.
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