A new synthesis of 4-methoxy-cyclopent-2-en-1-ones |
| |
Authors: | Arrigo Scettri |
| |
Institution: | Centro di Studio per la Chimica delle Sostanze Organiche Naturali del CNR c/o Dipartimento di Chimica, Università “La Sapienza”, P.le Aldo Moro 2, 00185 RomaItaly |
| |
Abstract: | 4-methoxy-cyclopent-2-en-1-ones are easily obtained through a simple procedure involving in the key-step the conversion of 2-furylcarbinols into 1,1,2-trimethoxy-al-kan-4-ones , a masked form of 1,4-dicarbonyl compounds, by treatment with Amberlyst H15 in methanolic solution. Then, the regeneration of the aldehydic function and a base-catalysed aldolic condensation lead in high yields to the final products . |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |
|