Convenient Synthesis of Spiro[benzo[d]pyrrolo[2,1‐b]thiazole‐3,2′‐indenes] Derivatives via Three‐Component Reaction |
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Authors: | Guoliang Shen Jing Sun Chaoguo Yan |
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Institution: | College of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou, Jiangsu 225002, China |
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Abstract: | The three‐component reaction of N‐phenacylbenzothiazolium bromides, aromatic aldehydes and indane‐1,3‐dione in ethanol at room temperature in the presence of triethylamine as base afforded functionalized spirobenzod]pyrrolo2,1‐b]thiazole‐3,2′‐indenes] in good yields and with high diastereoselectivity. The 1H NMR data and single crystal structure clearly indicated that the obtained spiro compounds predominately have one diastereoisomer. |
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Keywords: | multicomponent reaction nitrogen ylide spiro compound benzothiazole indan‐1 3‐dione |
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