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Preparation and characterization of antibacterial Au/C core-shell composite
Authors:Yan-Hong Gao  Nian-Chun Zhang  Huai-Hong Cai
Institution:a Department of Chemistry and Institute of Nanochemistry, Jinan University, 601 Huangpudadaoxi Road, Guangzhou 510632, Guangdong, PR China
b Centers for Disease Control and Prevention of Guangdong Province, Guangzhou 510300, Guangdong, PR China
Abstract:An environment-friendly oxidation-reduction method was used to prepare Au/C core-shell composite using carbon as core and gold as shell. The chemical structures and morphologies of Au/C core-shell composite and carbon sphere were characterized by X-ray diffraction, transmission electron microscope, energy dispersion X-ray spectrometry (EDS) and X-ray photoelectron spectroscopy (XPS). The antibacterial properties of the Au/C core-shell composite against Escherichia coli (E. coli), Staphylococcus aureus (S. aureus) and Candida albicans (C. albicans) were examined by the disk diffusion assay and minimal inhibition concentration (MIC) methods. In addition, antibacterial ability of Au/C core-shell composite was observed by atomic force microscope. Results demonstrated that gold homogeneously supported on the surface of carbon spheres without aggregation and showed efficient antibacterial abilities.
Keywords:Carbon spheres  Au/C  Core-shell structure  Antibacterial activity  Composite
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