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Antimicrobial activity of functionalized single‐walled carbon nanotube with herbal extract of Hempedu bumi
Abstract:The primary purpose of this study was to determine the antimicrobial activity of functionalized single‐walled carbon nanotube (SWNT) using an extract of the herb, Hempedu bumi. H bumi extract and H bumi extract complexed SWNT were evaluated for biological activities against Bacillus sp., (pathogen) Escherichia coli (opportunistic pathogen), and Aspergillus niger (pathogen). The formation of inhibition zones of these 3 microbes was measured to be evident for the functionalized SWNT with H bumi. Further, morphological and structural analyses were conducted to investigate the functionalized SWNT with H bumi using scanning electron microscopy, atomic force microscopy, X‐ray photoelectron spectroscopy, X‐ray powder diffraction, and Fourier transform infrared spectroscopy, well supporting the intact and crystalline nature of the SWNT. Fourier transform infrared spectroscopy result shows the highest peak at 3371.48 cm−1, representing an andrographolide group from the plant extract. An apparent clear zone has been noticed with SWNT conjugated H bumi extract, displaying a zone of inhibition larger than 1.0 cm against the tested microbes. The results indicate that SWNT has the potential for use as a carrier of components from plant extracts.
Keywords:antimicrobial  Aspergillus niger  Bacillus sp  Escherichia coli  Hempedu bumi  single‐walled carbon nanotube
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