| Abstract: | RuII compounds have been universally investigated due to their unique physical and chemical properties. In this paper, a new RuII compound based on 2,2′‐bipy and Hpmtz 2,2′‐bipy = 2,2′‐bipyridine, Hpmtz = 5‐(2‐pyrimidyl)‐1H‐tetrazole], namely Ru(2,2′‐bipy)2(pmtz)]PF6] · 0.5H2O was prepared and characterized by elemental analysis, IR and single‐crystal X‐ray diffraction. Ru(2,2′‐bipy)2(pmtz)]PF6] · 0.5H2O shows a mononuclear structure and forms a three‐dimensional network by non‐classic hydrogen bonds. The ability of generation of ROS (reactive oxygen species) makes it has a low phototoxicity IC50 (half‐maximal inhibitory concentration) after Xenon lamp irradiation on Hela cells in vitro. The results demonstrate that Ru(2,2′‐bipy)2(pmtz)]PF6] · 0.5H2O with high light toxicity and low dark toxicity may be a potential candidate for photodynamic therapy. |
