| 钠离子浓度对核小体纤维结构影响的Monte Carlo模拟 |
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| 引用本文： | 关治强,薛岩频,林海,何贵丽,吴晨旭.钠离子浓度对核小体纤维结构影响的Monte Carlo模拟[J].物理学报,2006,55(1):460-464. |
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| 作者姓名： | 关治强 薛岩频 林海 何贵丽 吴晨旭 |
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| 作者单位： | (1)厦门大学物理系软凝聚态研究室，厦门 361005; (2)厦门大学物理系软凝聚态研究室，厦门 361005;福建广播电视大学龙岩分校，龙岩 364000 |
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| 摘 要： | 通过核小体纤维模型的构建，利用Monto Carlo方法模拟其在各种钠离子浓度的溶液中结构变化的过程.模拟结果显示当溶液的钠离子浓度增大时，核小体由锯齿状结构转变为螺旋状结构.在常温所得到的核小体结构参数与实验结果接近，较好地解释了溶液中的钠离子浓度对核小体纤维结构的影响.
关键词：
核小体纤维
超螺旋结构
Monte Carlo方法
钠离子浓度
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| 关 键 词： | 核小体纤维 超螺旋结构 Monte Carlo方法 钠离子浓度 |
| 文章编号： | 1000-3290/2006/55(01)/0460-05 |
| 收稿时间： | 6/7/2005 12:00:00 AM |
| 修稿时间： | 2005-06-072005-06-22 |
Monte Carlo simulation of chromatin fiber conformation affected by ionic strength |
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| Guan Zhi-Qiang,Xue Yan-Pin,Lin Hai,He Gui-Li,Wu Chen-Xu.Monte Carlo simulation of chromatin fiber conformation affected by ionic strength[J].Acta Physica Sinica,2006,55(1):460-464. |
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| Authors: | Guan Zhi-Qiang Xue Yan-Pin Lin Hai He Gui-Li Wu Chen-Xu |
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| Institution: | 1 Department of Physics, Xiamen University, Xiamen 361005, China; 2 Longyan Radio and Tv University, FJ, Longyan 364000, China |
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| Abstract: | In this paper, using Monte Carlo simulation, we obtain different structures of chromatin fibers with different ionic concentration. The result shows that as the ionic concentration is increased, the fiber undergoes a conformational change from sawtooth state to super-helix state. The structural parameters obtained by simulation agree well with the experimental results, indicating that our model is useful in explaining the conformational change of chromatin fibers in different ionic solutions. |
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| Keywords: | ionic solutions super-helix state Monte Carlo solution density |
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