Synthesis of an isomer of the germacranolide isoaristolactone |
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Authors: | Gordon L. Lange Solomon So Mark Lautens Kevin Lohr |
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Affiliation: | Guelph-Waterloo Centre for Graduate Work in Chemistry Department of Chemistry, University of Guelph, Guelph, Ontario, N1G 2W1, Canada |
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Abstract: | Photocycloadditlon of (+)-isoplperltenone and cyclobutene-1-carboxylic acid gives an adduct which upon reduction with NaCNBH3 followed by thermolysis yields an isomer of isoaristolactone in an overall yield of 26%. |
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