Ethylenediamine diacetate-catalyzed three-component reaction for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones and their spirooxindole derivatives |
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| Authors: | Manchala NarasimhuluYong Rok Lee |
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| Institution: | School of Chemical Engineering and Technology, Yeungnam University, Gyeongsan 712-749, Republic of Korea |
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| Abstract: | Ethylenediamine diacetate (EDDA)-catalyzed one-pot syntheses of biologically interesting 2,3-dihydroquinazolin-4(1H)-ones and their spirooxindole derivatives from isatoic anhydride, amines, and benzaldehydes or isatins via a three-component condensation in aqueous media have been described. This method is of great value because of high yields and ease of handling. |
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| Keywords: | Three-component reaction 2 3-Dihydroquinazolin-4(1H)-one Spirooxindole |
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