Control of a double helix DNA assembly by use of cross-linked oligonucleotides |
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| Authors: | Endo Masayuki Majima Tetsuro |
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| Affiliation: | Institute of Scientific and Industrial Research, Osaka University, 8-1 Mihogaoka, Ibaraki, Osaka 567-0047, Japan. |
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| Abstract: | ![]()
Disulfide cross-linked oligonucleotides for connecting two DNA double helixes have been designed, synthesized, and characterized. Employing these cross-linked oligonucleotides, two double helixes can be arranged side by side, and the orientations can be controlled both in parallel and antiparallel ways by addition of a specific complementary DNA strand. |
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