A practical synthesis of [C4] N-benzylpiperazine from [C2] glycine |
| |
Authors: | Fredrik LakeChristian Linde |
| |
Institution: | Department of Medicinal Chemistry, AstraZeneca R&D Södertälje, SE-151 85 Södertälje, Sweden |
| |
Abstract: | A high yielding gram-scale synthesis of 13C4] N-benzylpiperazine for use as a convenient and versatile building block in isotope labeling studies of clinical drug candidates is reported. |
| |
Keywords: | 13C Isotope labeling N-Benzylpiperazine Glycine |
本文献已被 ScienceDirect 等数据库收录! |