Enthalpies of Solution of Some L-α-amino Acids in Aqueous Solutions of Urea at 298.15 K

The standard molar enthalpies of solution of glycine, L-α-alanine, L-α-valine and L-α-leucine in aqueous solutions of urea at 298.15 K were determined by calorimetry. The results obtained were used to calculate the heterogeneous enthalpic interaction coefficients between the zwitterions of the L-α-amino acids and a molecule of urea in water. The values of the resultant enthalpic interaction coefficients are interpreted in terms of the effects of the hydrophobic alkyl groups on the interactions between the zwitterions of the L-α-amino acids and a polar molecule of urea in aqueous solutions. This revised version was published online in August 2006 with corrections to the Cover Date.