An efficient approach to 3,4-disubstituted pyridin-2-ones. Formal synthesis of mappicine ketone |
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| Authors: | Lin Ching H Tsai Min R Wang Yung S Chang Nein C |
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| Affiliation: | Department of Chemistry, National Sun Yat-Sen University, Kaohsiung, Taiwan 804, Republic of China. |
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| Abstract: | ![]()
Treatment of 3,4-dihydro-3-tosylpyridin-2-one 5 with sodium hydride and then alkyl halides gave various 3,4-disubstituted pyridin-2-ones 6. Formal synthesis of mappicine ketone (1) was also reported. |
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