MR evaluation of breast lesions obtained by diffusion-weighted imaging with background body signal suppression (DWIBS) and correlations with histological findings |
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Authors: | Marco Moschetta Michele TelegrafoLeonarda Rella Arcangela CapolongoAmato Antonio Stabile Ianora Giuseppe Angelelli |
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Institution: | Interdisciplinary Department of Medicine – Section of Diagnostic Imaging – Aldo Moro University of Bari Medical School, Piazza Giulio Cesare 11, 70124 Bari, Italy |
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Abstract: | ObjectivesDiffusion imaging represents a new imaging tool for the diagnosis of breast cancer. This study aims to investigate the role of diffusion-weighted MRI with background body signal suppression (DWIBS) for evaluating breast lesions.Methods90 patients were prospectively evaluated by MRI with STIR, TSE-T2, contrast enhanced THRIVE-T1 and DWIBS sequences. DWIBS were analyzed searching for the presence of breast lesions and calculating the ADC value. ADC values of ≤ 1.44 × 10- 3 mm2/s were considered suspicious for malignancy. This analysis was then compared with the histological findings. Sensitivity, specificity, diagnostic accuracy (DA), positive predictive value (PPV) and negative (NPV) were calculated.ResultsIn 53/90 (59%) patients, DWIBS indicated the presence of breast lesions, 16 (30%) with ADC values of > 1.44 and 37 (70%) with ADC ≤ 1.44. The comparison with histology showed 25 malignant and 28 benign lesions. DWIBS sequences obtained sensitivity, specificity, DA, PPV and NPV values of 100, 82, 87, 68 and 100%, respectively.ConclusionDWIBS can be proposed in the MRI breast protocol representing an accurate diagnostic complement. |
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Keywords: | Magnetic resonance MRI Diffusion DWIBS Breast |
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