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α-Carbonyl Radicals for Total Synthesis of Natural Products |
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| Authors: | Chin-Kang Sha Tsong-Shin Jean Nei-Tung Yau Shih-Jung Huang Ruey-Torn Chiou Jenn-Fenn Young Shin-Hong Lih Wei-Hong Tseng |
| Abstract: | Intramolecular cyclization of α-carbonyl radicals to the trimethylsilylacetylenic side chain gives bicyclic vinylsilane ketones and enones. Application of this cyclization to total synthesis of (±)-modhephene is described. |
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