Chiral stationary phases based on cinchona alkaloids for the HPLC resolution of racemates |
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| Authors: | C. Rosini C. Bertucci D. Pini P. Altemura P. Salvadori |
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| Affiliation: | (1) Dipartimento di Chimica e Chimica Industriale, Centro di studio del CNR per le Macromolecole Stereordinate ed Otticamente Attive, via Risorgimento 35, I-56100 Pisa, Italy |
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| Abstract: | Summary The employment of three chiral stationary phases (CSPs) obtained by derivatizing γ-mercaptopropyl-silanized silica gel with quinine, quinidine and N-methyl-quinium iodide, for the separation of organic racemates, is presented. They are quite useful in the resolution of alkylarylcarbinols, binaphthyl derivatives, amides and other substances of pharmaceutical interest. |
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| Keywords: | Column liquid chromatography Chiral stationary phases Cinchona alkaloids |
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