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Efficient synthesis of 16-28 membered macrocyclic crown amides via ring closing metathesis |
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| Authors: | Yehia A Ibrahim Haider BehbehaniMaher R Ibrahim Rana N Malhas |
| Institution: | Department of Chemistry, Faculty of Science, Kuwait University, PO Box 5969, Safat 13060, Kuwait |
| Abstract: | Ring closing metathesis of suitable diamides containing 1,ω-dienes led to efficient synthetic approaches towards macrocylic polyoxadiamides 1-18 with 16-28 membered ring sizes in good to excellent yields using Grubbs' catalyst. |
| Keywords: | ring closing metathesis 1 ω-dienes bis-N-allyl-o-oxybenzamides bis-o-allyloxybenzamides bis-o-allyloxyanilides tetrabenzodiazapolyoxacycloalkenediones pentabenzodiazapolyoxa-cycloalkenediones |
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