Synthesis of hapten-phosphoramidites from 2′-deoxyuridine |
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| Authors: | Maciej Adamczyk Srinivasa Rao AkireddyPhillip G Mattingly Rajarathnam E Reddy |
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| Institution: | Department of Chemistry (09MD, Bldg AP20), Diagnostics Division, Abbott Laboratories 100 Abbott Park Road, Abbott Park, IL 60064-6016, USA |
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| Abstract: | A total of 11 novel phosphoramidites, 3a-d, 4a-d and 14a-c were prepared from 2′-deoxyuridine functionalized at 5 and 6-position of the pyrimidine ring with hapten reporter groups, e.g. adamantane, carbazole, dansyl and dabsyl, suitable for use in immunodetection nucleic acid testing assays. |
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| Keywords: | 2&prime -deoxyuridine haptens phosphoramidites |
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