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Synthesis of α-substituted 3-ulosonic acids from aldonolactones |
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| Authors: | René Csuk,Ulrike Franke Zhong Hu,Claus Krieger |
| Affiliation: | a Institut für Organische Chemie, Martin-Luther-Universität Halle-Wittenberg, Kurt-Mothes-Str. 2, D-06120 Halle (Saale), Germany b Max-Planck-Institut für Medizinische Forschung, Jahnstraße 29, D-69120 Heidelberg, Germany |
| Abstract: | Zinc-silver/graphite mediated Reformatsky-reaction of furanoid aldonolactones with α-bromo-esters allows the synthesis of α-substituted 3-ulosonic acids in high yields. |
| Keywords: | Reformatsky reactions aldonolactones |
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