Center for Integrated Protein Science, Lehrstuhl für Biochemie, Technische Universit?t München, Lichtenbergstrasse 4, 85747 Garching (Germany), Fax: (+49)?89‐289‐13363
Abstract:
The biosynthesis of natural products is a treasure trove of unusual reaction mechanisms. This Minireview summarizes recent work on the structure and mechanism of IspH protein, which catalyzes the reductive dehydroxylation of an allyl alcohol in a biosynthetic pathway leading to isoprenoid precursors.