Melamine trisulfonic acid-catalyzed N-formylation of amines under solvent-free conditions |
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| Authors: | Xiao Juan Yang Yong Sen Zhang |
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| Affiliation: | 1. College of Chemistry and Chemical Engineering, Xinxiang University, Xinxiang, 453003, Henan, China
2. The Third Affiliated Hospital, Xinxiang Medical University, Xinxiang, 45300, Henan, China
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| Abstract: | A highly convenient method for N-formylation of amines via treatment by formic acid in the presence of melamine trisulfonic acid as a catalyst has been developed. This method showed improvements over previous reports in terms of yield, reaction time and chemoselectivity. |
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