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Using an electrical potential to reversibly switch surfaces between two states for dynamically controlling cell adhesion |
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| Authors: | Ng Cheuk Chi Albert Magenau Astrid Ngalim Siti Hawa Ciampi Simone Chockalingham Muthukumar Harper Jason Brian Gaus Katharina Gooding John Justin |
| Affiliation: | School of Chemistry and Australian Centre for NanoMedicine, The University of New South Wales, Sydney NSW 2052, Australia. |
| Abstract: | Smart surfaces presenting both antifouling molecules with a charged functional group at their distal end, and molecules that are terminated by RGD peptides for cell adhesion, were fabricated and characterized (see picture). By applying potentials of +300 or -300?mV, the surfaces could be dynamically switched to make the peptide accessible or inaccessible to cells. |
| Keywords: | cell adhesion hydrosilylation monolayers surface chemistry |
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