Determination of Paracetamol Based on its Quenching Effect on the Photoluminescence of CdTe Fluorescence Probes |
| |
Authors: | Li Li Yaxiang Lu Yaping Ding Yu Cheng Wanchen Xu Fenfen Zhang |
| |
Institution: | (1) Department of Chemistry, Shanghai University, Shanghai, 200444, People’s Republic of China; |
| |
Abstract: | L-Cysteine capped CdTe nanoparticles (NPs) were synthesized in aqueous medium, and their application as fluorescence probes
in the determination of paracetamol was studied. The L-cysteine capped CdTe NPs were characterized by transmission electron
microscopy, X-ray diffraction spectrometry, spectrofluorometry, ultraviolet-visible and Fourier transform infrared spectrometry.
Based on the distinct fluorescence quenching of CdTe fluorescence probes in the presence of paracetamol, a simple, rapid and
specific method for paracetamol determination was presented. Under optimum conditions, the relative fluorescence intensity
of CdTe NPs was linearly proportional to paracetamol concentration from 1.0 × 10−8 mol/L to 1.6 × 10−7 mol/L with a detection limit of 4.2 × 10−9 mol/L. The proposed method was applied to detect paracetamol in commercial tablets with satisfactory results. |
| |
Keywords: | |
本文献已被 PubMed SpringerLink 等数据库收录! |
|