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| D-氨基葡萄糖N-位和苷羟基化学改性的研究进展 | |
| 引用本文： | 刘玮炜,李曲祥,程峰昌,张强,霍云峰.D-氨基葡萄糖N-位和苷羟基化学改性的研究进展[J].化学通报,2014,77(11):1064-1075. |
| 作者姓名： | 刘玮炜 李曲祥 程峰昌 张强 霍云峰 |
| 作者单位： | 1. 淮海工学院化学工程学院 连云港222005;中国矿业大学化工学院 徐州221116;江苏省海洋资源开发研究院 连云港222005 2. 中国矿业大学化工学院 徐州221116 3. 淮海工学院化学工程学院 连云港222005 |
| 基金项目： | 江苏省高校自然科学研究重大项目（10KJA170003）资助；江苏省高校科研成果产业化推进项目(No. JHB2012-60)资助；连云港市科技攻关项目(CG1105)及江苏高校优势学科建设工程资助项目资助. |
| 摘 要： | D-氨基葡萄糖作为一种天然的氨基单糖,广泛存在于各种生物体内。它是甲壳素的最终水解产物,分子中含有1个氨基和4个羟基。由于其结构的特殊性,对它及其衍生物的研究备受关注,其产品已应用于诸多领域,如生物和医药等。本文综述了近年来对其的N-位和苷羟基进行化学改性的研究进展,着重介绍了选择性化学修饰的方法和发展动向。 |
| 关 键 词： | D-氨基葡萄糖 化学改性 方法 |
| 收稿时间： | 2014/3/17 0:00:00 |
| 修稿时间： | 5/5/2014 12:00:00 AM |
Progress in Chemical Modification of D-glucosamine N-site and Glycoside Hydroxy |
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| liuweiwei,liquxiang,chengfengchang,zhangqiang and huoyunfeng.Progress in Chemical Modification of D-glucosamine N-site and Glycoside Hydroxy[J].Chemistry,2014,77(11):1064-1075. | |
| Authors: | liuweiwei liquxiang chengfengchang zhangqiang and huoyunfeng |
| Institution: | Liu Weiwei;Li Quxiang;Cheng Fengchang;Zhang Qiang;Huo Yunfeng;Department of Chemical Engineering,Huaihai Institute of Technology;School of Chemical Engineering and Technology,China University of Mining and Technology;Jiangsu Institute of Marine Resources; |
| Abstract: | D-Glucosamine as a natural amino monosaccharide widely exists in a variety of organisms, which is the final degradation product of chitin. The molecule contains one amido and four hydroxyls. It is of great significance to research on it due to the special nature of its structure. Currently, D-Glucosamine and its derivatives are paied more attention to by scientists, and its products have been applied in many fields, such as biology, medicine and so on. Therefore, the review has a closer look at chemical modification of D-Glucosamine N-site and glycoside hydroxy. The methods of selective chemical modification of D-glucosamine are especially introduced. |
| Keywords: | D-Glucosamine Chemical modification Approach |
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