Shorter and modular synthesis of hemicryptophane-tren derivatives |
| |
Authors: | Chatelet Bastien Payet Elina Perraud Olivier Dimitrov-Raytchev Pascal Chapellet Laure-Lise Dufaud Véronique Martinez Alexandre Dutasta Jean-Pierre |
| |
Institution: | Laboratoire de Chimie, CNRS, E?cole Normale Supe?rieure de Lyon, 46 Alle?e d'Italie, F-69364 Lyon, France. |
| |
Abstract: | Hemicryptophanes are host molecules with many applications as supramolecular catalysts or in ion selective recognition. A very convenient and efficient modular approach for the synthesis of hemicryptophane-tren (tren, tris(2-aminoethyl)-amine) derivatives has been developed. For instance, hemicryptophane 1 was synthesized at the gram scale in four steps from vanillyl alcohol compared to the previous seven-step procedure. The size, shape, and functionalities of the molecular cavity were also easily modified. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|