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Studies on Carbohydrates ⅩⅩⅧ. Synthesis of Key Intermediates of Oligosaccharides Related to Serratia marcescens O10 Antigen
作者姓名:Ke Qin ZHANG   Jian Min MAO   Hong Min CHEN   Meng Shen CAI(School of Pharmaceutical Sciences  Beijing Medical University  Beijing 100083)
作者单位:School of Pharmaceutical Sciences,Beijing Medical University,Beijing 100083
摘    要:
TheO-antigenofbacteriacanbeusedasahaptenandvaccine.Preparationofanantigeninv0lvesthesynthesisofacorrespondinghaPtenbearingeithernarrow0rwiderspeci-ficity.Generally,fragmentsofcarbohydratechainsbearingthes0-calledcompleterepeatingunitareemployedashaPtens.Synthesis0foligosaccharides,whichareveryspecificfragments,isatpresentoneoftheimP0rtantaspectsofcarb0hydratechemistry.TheS.marcescensOlOantigenhasbeenisolatedfromtheLPSofthereferencesKain(C.D.C.l287-54)ofS.marcescens.Itsbiol0gicalrepeatun…

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