发中微量元素与体外模拟血栓形成关系38例探讨

采用上海医科大学生物力学研究中心提供的Ｃａｓｔ体外模拟血栓仪，筛选出３８例血栓指数Ｑ值大于２０的阳性患者，测定其发中微量元素Ｚｎ、Ｃｕ、Ｆｅ、Ｐｂ、Ｃｕ含量及Ｚｎ／Ｃｕ比。另设正常血栓指数Ｑ值（男＜１０，女＜１２）为健康对照组共３０例。检测结果表明阳性组发中Ｚｎ、Ｐｂ含量明显高于对照组，而发Ｃｕ却显著低于对照组；Ｚｎ／Ｃｕ比值也明显高于对照组，但发Ｆｅ差异不明显，提示发中Ｚｎ，Ｃｕ的变化，尤其Ｚｎ／Ｃｕ比值的增高可作体内隐性血栓存在的预兆，该指标可与Ｑ值相互参考作为临床检测手段之一。

Study on Relation of Trace Elements is Hair with Formation of Cast Simulated Thrombus

The trace elements Zn,Cu, Fe, Ph in hair from 38 cases of patients,whose cast simulated thrombus indexes Q are higher than 20, were examined. The results showed that Zn and Pb in the patients were obviously higher, while Cu was obviously lower than in control group,the Zn/Cu was obviously higher than the control group, too. It is discovered that Zn and Cu have a close relationship with latent thrombus (P<0. 05). All these studies have enabled to conclude that the increase of Zn/Cu ratio in hair is a significant index of the existence ofcatent thrombus.