Task Specific Onium Salts and Ionic Liquids as Soluble Supports in Grieco ’s Multicomponent Synthesis of Tetrahydroquinolines |
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Authors: | Fatima Hassine Said Gmouh Mathieu Pucheault and Michel Vaultier |
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Institution: | (1) UMR CNRS 6510, 263 Avenue du G?n?ral Leclerc, Campus de Beaulieu, Universit? de Rennes 1, 35042 Rennes Cedex, France |
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Abstract: | In this work was presented an application of the use of task specific onium salts (TSOSs) as soluble supports in Grieco’s multicomponent synthesis of tetrahydroquinolines. These soluble supports are of wide applicability and combine advantages
of solid phase synthesis without its limitations with those of solution phase chemistry. After a simple washing step, products
were cleaved from the supports and obtained in pure form and good yields. |
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