MethylN-(benzylsulfonyl)oxamate as a probable intermediate in the synthesis of 4-hydroxy-5-phenyl-3(2H)-isothiazolone 1,1-dioxide from phenylmethanesulfamide and dimethyl oxalate in the presence of bases

The formation of 4-hydroxy-5-phenyl-3(2H)-isothiazolone 1,1-dioxide from phenylmethanesulfamide and dimethyl oxalate under the action of bases is apparently a two-stage process involving the formation of linear methylN-(benzylsulfonyl)oxamate followed by its cyclization. A stable complex of the heterocycle with dimethylformamide was synthesized. Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 2, pp. 396–398, February, 1999.