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Tyrosine 92 of aristolochene synthase directs cyclisation of farnesyl pyrophosphate
Authors:Calvert Melanie J  Taylor Susan E  Allemann Rudolf K
Affiliation:School of Chemical Sciences, University of Birmingham, Edgbaston, Birmingham, UK B15 2TT.
Abstract:
A mutant of Aristolochene Synthase (AS), in which Tyr 92 was replaced by Val, produced the alicyclic beta-(E)-farnesene as the major product, indicating that cyclisation of FPP is controlled by Tyr 92 in AS.
Keywords:
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