超分子结构二氟尼柳插层镁铝水滑石的合成与表征

采用离子交换和共沉淀两种不同方法将二氟尼柳插入镁铝水滑石层间，得到一种新型的有机-无机层状复合材料。通过X射线粉末衍射、红外光谱、元素分析和热重-差热等手段对材料进行了表征。结果表明，离子交换法和共沉淀法成功地将二氟尼柳插入水滑石，得到的材料层状结构完整、晶相单一，且层间距均大于二氟尼柳分子尺寸，扩大为1.81～2.14 nm；二氟尼柳插入后，复合水滑石材料的热稳定性大幅度提高。客体二氟尼柳与主体层板之间存在超分子作用力，二氟尼柳分子的羧基与水滑石层板之间相互作用，以双层倾斜交替地排列于层板之间。此外，根据其超分子作用力建立了二氟尼柳插层镁铝水滑石的超分子结构模型。

Synthesis and Characterization of Magnesium Aluminum Layered Double Hydroxides Intercalated with Diflunisal

A new organic-inorganic hybrid material was obtained by the intercalation of the drug diflunisal into magnesium aluminum layered double hydroxides (LDHs). The intercalation was performed by ion exchange and co-precipitation method, respectively. The complex materials were characterized using powder X-ray diffractometry (XRD), Fourier-transform infrared (FTIR), ICP and TG-DTA. The results show that the interlayer spaces of the materials are expanded to 1.81~2.14 nm and the thermal stability of material increases after the intercalation of diflunisal. A supramolecular structure model for Diflunisal-LDHs is suggested, i.e. diflunisal molecules form a titled alternate bilayer with carboxylate groups pointing towards the LDHs layers.